Pathway Type:
Signaling
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Figure contributed by Greg Gurda and John Williams
Reviews
- The Calcineurin-NFAT Pathway and Regulation of Pancreatic Function - Greg Gurda, Tejan St John, and John A Williams
- Regulation of Normal and Adaptive Pancreatic Growth - John A Williams, University of Michigan
Components
- Calcineurin
- CCKR1
- CRHSP-24
- Dynamin
- Gq/11
- Inositol 1,4,5-trisphosphate receptors (InsP3R)
- MEFs
- NFATs
- RCAN1
- Rgs2
Methods
- Ca2+ activated nuclear translocation of NFATs