From 2008 to 2016, I worked as a research assistant in the lab of Dr. Sohail Husain. Our lab studied the biochemical pathways involved in the early stages of pancreatic disease, with particular focus on pancreatitis. My goals were to understand how specific insults affect calcium signals within the pancreatic acinar cell. In particular, we examined the effects of alcohol, bile acids, radiocontrast, and HDAC inhibitors; all of which are known to cause disease in humans. Calcium is a critical mediator of early pathological events within the pancreas. Understanding the mechanism by which aberrant calcium signals lead to disease is a main focus of our lab, and critical for improving the way we treat pancreatitis in the clinical setting.
In 2016, I began my PhD at Case Western Reserve University, under the mentorship of Dr. Sanford Markowitz in the Department of Genetics. Currently, our lab investigates molecular abnormalities in colon cancer, the functions of positive and negative regulatory growth factors, and the role of genomic instability in inherited and sporadic colon cancers.